Long COVID (PASC): Background
internal_protocolobservational · status: needs_provider_reviewDetails
Author: Axiom Knowledge Base
Citation: Internal reference summary compiled for the Axiom knowledge base (2026).
File: signed link
Summary (generated — provider review required)
Post-acute sequelae of SARS-CoV-2 (Long COVID/PASC) encompasses fatigue, PEM, dysautonomia, cognitive impairment, and exercise intolerance, with proposed mechanisms including immune dysregulation, endothelial/microclot involvement, viral persistence, and mitochondrial impairment. Substantial phenotype overlap with ME/CFS. Background for provider interpretation only — evidence evolving and largely observational.
The original source document remains the source of truth. Generated summaries are not authoritative.
Linked assets (0) · phenotypes (2)
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Phenotypes: dysautonomia, immune_dysregulation
Findings (1) · awaiting review (0)
mechanism · pending
Post-acute sequelae of SARS-CoV-2 (Long COVID/PASC) encompasses fatigue, PEM, dysautonomia, cognitive impairment, and exercise intolerance, with proposed mechanisms including immune dysregulation, endothelial/microclot involvement, viral persistence, and mitochondrial impairment.
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