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Epitalon — Peptide Dosing Protocols reference

patient_educationexpert_opinion · status: needs_provider_review
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Epitalon Peptide Protocol Guide: Dosing, Reconstitution & Safety (2026) Shop Protocols Stacks A–Z Index Email Updates Home Protocols Epitalon Peptide Protocol Guide: Dosing, Reconstitution & Safety (2026) Protocol / Research Dosing Guide Epitalon Peptide Protocol Guide: Dosing, Reconstitution & Safety (2026) An evidence-based Epitalon peptide guide covering Epithalon/AEDG dosing context, reconstitution math, cycle length, supplies, side effects, and telomere and circadian research boundaries. By Garret Grant · Founder & Lead Researcher · Last reviewed June 2026 · Share Supplier Pick Copy code SAVE10 Copy code SAVE10 Verified Supplier Link Verified Supplier Link Ventra Sciences Epithalon View Ventra Table of Contents View Supplies Quick Start Dosing Protocol & Schedule Supplies Needed Reconstitution Guide How It Works Who Should Avoid Side Effects & Safety Expected Timeline Clinical Evidence Context Storage & Handling Troubleshooting Regulatory Status Comparison Related Protocols FAQ References Epitalon Quick Start Epitalon, also spelled epithalon, is a small peptide made of four amino acids in a row: Ala-Glu-Asp-Gly. You may also see it written as AEDG .

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Linked assets (6) · phenotypes (0)

evidence_reference, dosing_reference, safety_reference, mechanism

Findings (102) · awaiting review (76)
mechanism · pending
Khavinson V, Goncharova N, Lapin B Synthetic tetrapeptide epitalon restores disturbed neuroendocrine regulation in s
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0 mg vial, 5.0 mL of BAC water gives 10 mg/mL.
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Q5: How do you reconstitute a 50 mg epitalon vial?
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Epitalon Peptide Protocol Guide: Dosing, Reconstitution & Safety (2026) Shop Protocols Stacks A–Z Index Email Updates Home Protocols Epitalon Peptide Protocol Guide: Dosing, Reconstitution & Safety (2026) Protocol / Research Dosing Guide Epitalon Peptide Protocol Guide: Dosing, Reconstitution & Safety (2026) An evidence-based Epitalon peptide guide covering Epithalon/AEDG dosing context, reconstitution math, cycle length, supplies, side effects, and telomere and circadian research boundaries.
dosing · pending
By Garret Grant · Founder & Lead Researcher · Last reviewed June 2026 · Share Supplier Pick Copy code SAVE10 Copy code SAVE10 Verified Supplier Link Verified Supplier Link Ventra Sciences Epithalon View Ventra Table of Contents View Supplies Quick Start Dosing Protocol & Schedule Supplies Needed Reconstitution Guide How It Works Who Should Avoid Side Effects & Safety Expected Timeline Clinical Evidence Context Storage & Handling Troubleshooting Regulatory Status Comparison Related Protocols FAQ References Epitalon Quick Start Epitalon, also spelled epithalon, is a small peptide made of four amino acids in a row: Ala-Glu-Asp-Gly.
dosing · pending
This page covers the reported dosing context, how the vial is mixed, supplies, and safety .
outcome · pending
For a broader benefits and evidence overview, read the Epitalon guide on Peptide Advisors .
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Reconstitute Add 2.0 mL BAC water to a 10 mg vial.
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Reported schedule Short cycles: about 5-10 mg/day for 10-20 days, 1-2 times a year.
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Easy measuring On a 5 mg/mL mix, 5 mg equals 1.0 mL, which is 100 units on a U-100 syringe.
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Timing Many reported protocols use evening dosing to line up with the natural melatonin rhythm.
regulatory · pending
Research status Not FDA-approved.
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Educational research reference This page reports dosing context from published research and community protocols.
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Epitalon Dosing Protocol & Schedule Epitalon dosing is unusual because the cycles are short and spaced far apart.
dosing · pending
Most peptides are dosed for weeks or months.
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Both deliver a similar total dose per cycle.
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Two commonly reported epitalon cycle patterns Pattern Standard short cycle Daily amount 5 mg/day (evening, SubQ) Days on 20 days Repeat 2-3 times per year Pattern Condensed cycle Daily amount 10 mg/day
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(evening, SubQ) Days on 10 days Repeat 2-3 times per year Pattern Daily amount Days on Repeat Standard short cycle 5 mg/day (evening, SubQ) 20 days 2-3 times per year Condensed cycle 10 mg/day (evening, SubQ) 10 days 2-3 times per year Both patterns add up to roughly 100 mg per cycle.
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Higher single doses (up to ~50 mg/day in some animal-era work) have not shown clearer results in the available research.
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Almost all reported protocols use a subcutaneous (SubQ) injection, meaning a small injection into the fat layer just under the skin.
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Some community sources mention an intranasal spray version, but that route is far less studied and dosing equivalence is unclear.
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Evidence boundary There is no large, blinded human trial that tested a specific epitalon injection dose against placebo for telomere length.
safety · pending
Anyone who is pregnant or breastfeeding — there is no safety data for these groups.
dosing · pending
The schedules above come from older Russian research programs and self-reported community use, not from a modern FDA-style dosing trial.
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Epitalon Supplies Needed Supply math below is based on the standard reported schedule: 5 mg per day from a 10 mg vial reconstituted with 2.0 mL BAC water, for a 20-day cycle.
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One 10 mg vial covers two daily doses, so a 20-day cycle uses about 10 vials.
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Peptide Vials (10 mg) Based on 5 mg/day.
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A 10 mg vial covers 2 daily doses.
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50 mg vials cover 10 doses each, so a full 20-day cycle is 2 of the 50 mg size instead.
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Cycle length Planning note 10-day cycle 5 x 10 mg vials 10 doses at 5 mg/day.
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20-day cycle 10 x 10 mg vials 20 doses at 5 mg/day.
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10-day cycle 5 x 10 mg vials 10 doses at 5 mg/day.
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Prefer 1 mL / 100-unit syringes since a 5 mg dose is a full 1.0 mL draw.
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Bacteriostatic Water Use 2.0 mL per 10 mg vial.
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Cycle length Planning note 10-day cycle 1 x 10 mL bottle 5 vials use 10 mL total.
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20-day cycle 2 x 10 mL bottles 10 vials use 20 mL total.
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10-day cycle 1 x 10 mL bottle 5 vials use 10 mL total.
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If you use 50 mg vials,
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Epitalon reconstitution math (U-100 syringe) Vial size 10 mg BAC water added 2.0 mL Concentration 5 mg/mL 5 mg dose 1.0 mL = 100 units 10 mg dose Whole vial Vial size 50 mg BAC water added 5.0 mL Concentration 10 mg/mL 5 mg dose 0.5 mL = 50 units 10 mg dose 1.0 mL = 100 units Vial size BAC water added Concentration 5 mg dose 10 mg dose 10 mg 2.0 mL 5 mg/mL 1.0 mL = 100 units Whole vial 50 mg 5.0 mL 10 mg/mL 0.5 mL = 50 units 1.0 mL = 100 units These are two clean, easy-to-measure mixes.
dosing · pending
Other volumes work too; the calculator handles any vial size and target dose.
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