MCAS / immune dysregulation — anaphylaxis history (critical safety) — draft

Provider-guided draft · every step is provider-entered and monitored — nothing auto-prescribes.

Provider-guided builder. No autonomous selection or dosing. All plan text is provider-entered; dosing references are source-attributed, provider-reviewed material only. Not patient-facing.

Plan details

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Apply an approved template

Copies the template’s components into this plan as drafts for your review — nothing is auto-prescribed; you still edit and sign off.

Components

1 step

LL-37evidence 0

Provider-only dosing references:

100 mcg SC daily or every other day — Practitioner Peptide Dosing Reference (commonly published ranges) (Compiled practitioner reference) · internal_protocol · NOT reviewed

Sign-off

Audit history (3)

2026-06-14 00:42:46 · update_component
2026-06-14 00:42:46 · add_component
2026-06-14 00:42:45 · create_plan by dr_demo — Draft created

Applies to

draft1 components0 evidence links

Safety check

critical: 1 critical safety flag(s) present — review before sign-off.

high: 2 high-priority safety flag(s) present — review before sign-off.

caution: 3 missing safety item(s) — confirm before sign-off.

caution: Component "peptide #1" has no linked evidence/source.

Patient context

Captured at draft creation.

Phenotype

{
  "scores": {
    "gut_immune": 0,
    "dysautonomia": 0,
    "babesia_pattern": 0,
    "connective_tissue": 0,
    "mold_cirs_pattern": 5,
    "neuroinflammation": 0,
    "bartonella_pattern": 0,
    "immune_dysregulation": 73,
    "metabolic_dysfunction": 0,
    "mitochondrial_dysfunction": 0
  },
  "primary": "immune_dysregulation",
  "secondary": "mold_cirs_pattern",
  "recoveryStage": "improving"
}

Safety

{
  "highFlags": [
    {
      "category": "reaction_history",
      "description": "High-reactivity or severe flare history may increase risk of intolerance."
    },
    {
      "category": "reaction_history",
      "description": "MCAS/high-reactivity history may increase risk of intolerance."
    }
  ],
  "criticalFlags": [
    {
      "category": "reaction_history",
      "description": "Anaphylaxis history is a critical reaction-risk consideration."
    }
  ],
  "overallRiskLevel": "Critical Review Priority",
  "overallRiskScore": 88,
  "missingInformation": [
    "allergy_history_confirmed",
    "pregnancy_status_confirmed",
    "infection_status_confirmed"
  ],
  "monitoringConsiderations": [
    "Allergy and reaction history review",
    "Physician review before protocol selection"
  ]
}

Labs

{
  "systems": {
    "immune": 40,
    "hormonal": 0,
    "metabolic": 0,
    "nutritional": 0,
    "inflammatory": 0,
    "mitochondrial": 0,
    "detoxification": 0,
    "connective_tissue": 0,
    "neuroinflammatory": 0
  },
  "confidence": 0.29,
  "missingMarkers": [
    "hscrp",
    "esr",
    "ferritin",
    "fibrinogen",
    "neutrophils",
    "lymphocytes",
    "monocytes",
    "basophils",
    "iga",
    "igm",
    "lactate",
    "pyruvate",
    "ck",
    "tsh",
    "free_t3",
    "free_t4",
    "reverse_t3",
    "testosterone",
    "estradiol",
    "progesterone",
    "dhea_s",
    "am_cortisol",
    "fasting_glucose",
    "fasting_insulin",
    "hba1c",
    "triglycerides",
    "hdl",
    "ldl",
    "b12",
    "folate",
    "iron",
    "iron_saturation",
    "magnesium",
    "zinc",
    "copper",
    "ast",
    "alt",
    "ggt",
    "bilirubin",
    "albumin",
    "creatinine",
    "egfr"
  ],
  "abnormalMarkers": [
    {
      "flag": "high",
      "value": 8,
      "marker_name": "eosinophils"
    }
  ]
}

Outcomes

{
  "trends": {
    "pem": [],
    "pain": [
      {
        "date": "2026-02-05T09:00:00+00:00",
        "value": 4
      },
      {
        "date": "2026-03-07T09:00:00+00:00",
        "value": 3
      }
    ],
    "sleep": [
      {
        "date": "2026-02-05T09:00:00+00:00",
        "value": 4
      },
      {
        "date": "2026-03-07T09:00:00+00:00",
        "value": 5
      }
    ],
    "fatigue": [
      {
        "date": "2026-02-05T09:00:00+00:00",
        "value": 6
      },
      {
        "date": "2026-03-07T09:00:00+00:00",
        "value": 5
      }
    ],
    "brain_fog": [],
    "functional": [
      {
        "date": "2026-02-05T09:00:00+00:00",
        "value": 45
      },
      {
        "date": "2026-03-07T09:00:00+00:00",
        "value": 55
      }
    ]
  },
  "baselineVsCurrent": [
    {
      "metric": "fatigue_score",
      "current": 5,
      "baseline": 6
    },
    {
      "metric": "brain_fog_score",
      "current": null,
      "baseline": null
    },
    {
      "metric": "pain_score",
      "current": 3,
      "baseline": 4
    },
    {
      "metric": "sleep_quality_score",
      "current": 5,
      "baseline": 4
    },
    {
      "metric": "pem_score",
      "current": null,
      "baseline": null
    },
    {
      "metric": "work_capacity_percent",
      "current": 55,
      "baseline": 45
    }
  ],
  "clinicalImprovementScore": 56,
  "functionalImprovementScore": 54
}