ME/CFS — mitochondrial + PEM — draft

Provider-guided draft · every step is provider-entered and monitored — nothing auto-prescribes.

Provider-guided builder. No autonomous selection or dosing. All plan text is provider-entered; dosing references are source-attributed, provider-reviewed material only. Not patient-facing.

Plan details

Add protocol component

Apply an approved template

Copies the template’s components into this plan as drafts for your review — nothing is auto-prescribed; you still edit and sign off.

Components

1 step

MOTS-cevidence 0

Provider-only dosing references:

5-10 mg SC 2-3 times weekly — Practitioner Peptide Dosing Reference (commonly published ranges) (Compiled practitioner reference) · internal_protocol · NOT reviewed

Sign-off

Audit history (3)

2026-06-14 00:42:39 · update_component
2026-06-14 00:42:39 · add_component
2026-06-14 00:42:38 · create_plan by dr_demo — Draft created

Applies to

draft1 components0 evidence links

Safety check

caution: 2 missing safety item(s) — confirm before sign-off.

caution: Component "peptide #1" has no linked evidence/source.

Patient context

Captured at draft creation.

Phenotype

{
  "scores": {
    "gut_immune": 0,
    "dysautonomia": 19,
    "babesia_pattern": 0,
    "connective_tissue": 0,
    "mold_cirs_pattern": 0,
    "neuroinflammation": 15,
    "bartonella_pattern": 0,
    "immune_dysregulation": 0,
    "metabolic_dysfunction": 0,
    "mitochondrial_dysfunction": 96
  },
  "primary": "mitochondrial_dysfunction",
  "secondary": "dysautonomia",
  "recoveryStage": "stable"
}

Safety

{
  "highFlags": [],
  "criticalFlags": [],
  "overallRiskLevel": "Low Review Priority",
  "overallRiskScore": 0,
  "missingInformation": [
    "pregnancy_status_confirmed",
    "infection_status_confirmed"
  ],
  "monitoringConsiderations": [
    "Physician review before protocol selection"
  ]
}

Labs

{
  "systems": {
    "immune": 0,
    "hormonal": 0,
    "metabolic": 0,
    "nutritional": 0,
    "inflammatory": 0,
    "mitochondrial": 20,
    "detoxification": 0,
    "connective_tissue": 0,
    "neuroinflammatory": 10
  },
  "confidence": 0.37,
  "missingMarkers": [
    "hscrp",
    "esr",
    "fibrinogen",
    "wbc",
    "neutrophils",
    "lymphocytes",
    "monocytes",
    "eosinophils",
    "basophils",
    "igg",
    "iga",
    "igm",
    "pyruvate",
    "free_t3",
    "free_t4",
    "reverse_t3",
    "testosterone",
    "estradiol",
    "progesterone",
    "dhea_s",
    "fasting_glucose",
    "fasting_insulin",
    "hba1c",
    "triglycerides",
    "hdl",
    "ldl",
    "folate",
    "iron",
    "iron_saturation",
    "magnesium",
    "zinc",
    "copper",
    "ast",
    "alt",
    "ggt",
    "bilirubin",
    "albumin",
    "creatinine",
    "egfr"
  ],
  "abnormalMarkers": [
    {
      "flag": "high",
      "value": 2.6,
      "marker_name": "lactate"
    },
    {
      "flag": "high",
      "value": 210,
      "marker_name": "ck"
    }
  ]
}

Outcomes

{
  "trends": {
    "pem": [
      {
        "date": "2026-02-20T09:00:00+00:00",
        "value": 9
      }
    ],
    "pain": [
      {
        "date": "2026-02-20T09:00:00+00:00",
        "value": 5
      }
    ],
    "sleep": [
      {
        "date": "2026-02-20T09:00:00+00:00",
        "value": 3
      }
    ],
    "fatigue": [
      {
        "date": "2026-02-20T09:00:00+00:00",
        "value": 9
      }
    ],
    "brain_fog": [
      {
        "date": "2026-02-20T09:00:00+00:00",
        "value": 6
      }
    ],
    "functional": [
      {
        "date": "2026-02-20T09:00:00+00:00",
        "value": 15
      }
    ]
  },
  "baselineVsCurrent": [
    {
      "metric": "fatigue_score",
      "current": 9,
      "baseline": 9
    },
    {
      "metric": "brain_fog_score",
      "current": 6,
      "baseline": 6
    },
    {
      "metric": "pain_score",
      "current": 5,
      "baseline": 5
    },
    {
      "metric": "sleep_quality_score",
      "current": 3,
      "baseline": 3
    },
    {
      "metric": "pem_score",
      "current": 9,
      "baseline": 9
    },
    {
      "metric": "work_capacity_percent",
      "current": 15,
      "baseline": 15
    }
  ],
  "clinicalImprovementScore": 50,
  "functionalImprovementScore": 50
}