GHK-Cu

GHK-Cu (copper tripeptide-1) is a naturally occurring tripeptide-copper complex studied in tissue-repair and skin research. Lyophilized powder. Reconstitute with bacteriostatic water for in-vitro research. Store at -20°C. Certificate of Analysis attached to this listing.

Copper-binding peptide with repair signaling.

GHK-Cu does two things at once. It carries copper into cells where copper-dependent enzymes need it, and the GHK fragment itself acts as a signaling peptide that influences gene expression in fibroblasts and other tissue cells. That dual role is part of why the research base touches so many systems: skin, hair follicles, wound beds, lung, gut, and bone in animal and cell models.

Mechanistically, GHK-Cu has been shown to stimulate collagen and elastin synthesis in dermal fibroblasts, increase decorin (a small proteoglycan that helps regulate collagen organization), and influence matrix metalloproteinases and their inhibitors. Broad gene-mapping work led by Pickart and colleagues reported modulation of thousands of genes, with roughly a third of human gene patterns shifting toward expression states associated with younger or healthier tissue.

The mechanism story is broad, but most of it is built on cell and animal models. The strongest human-level translation is in topical skin biology. Injectable systemic translation is still mostly indirect. [Source: Peptide Dosing Protocols]

Amino sequence: Gly-His-Lys · Cu²⁺ (GHK-Cu)

COA: View certificate (batch TET-4892-A) →

Teton Labs product catalog · research-use compound data.