AXIOMD · Clinical Intelligence

Screening & flagging for physician review only. Axiom does not diagnose, treat, approve, or deny. It surfaces considerations for your judgment.

Cancer history

Current cancercriticalActive cancer requires physician review before any protocol consideration.Active oncology carehighActive oncology care requires coordination and physician review.Prior cancerhighPrior cancer history requires physician review before regenerative or immune-modulating protocol consideration.

Autoimmune

Recent autoimmune flarehighRecent autoimmune flare may affect immune-modulating safety.Autoimmune diagnosiscautionAutoimmune diagnosis warrants physician review of immune considerations.Immunomodulating medicationscautionImmunomodulating medication use warrants interaction review.

Pregnancy / fertility

PregnantcriticalPregnancy requires physician review; many interventions are contraindicated.BreastfeedinghighBreastfeeding requires physician review of exposure considerations.Trying to conceivecautionConception planning warrants reproductive safety review.Fertility treatmentcautionActive fertility treatment warrants coordination and review.

Immunosuppression

Transplant historyhighTransplant history requires immune-status physician review.Biologic medicationshighBiologic medication use requires interaction and immune review.Chemotherapy historyhighChemotherapy history requires physician review.Immune deficiencyhighImmune deficiency requires physician review.Steroid usecautionSteroid use warrants immune and interaction review.

Cardiac

Heart failurehighHeart failure history requires cardiac review.ArrhythmiahighArrhythmia history requires cardiac review.SyncopehighSyncope history requires cardiac/neuro review.Chest painhighChest pain requires physician evaluation.Uncontrolled hypertensioncautionUncontrolled hypertension warrants cardiac monitoring.PalpitationscautionPalpitations warrant cardiac review.

Kidney

Kidney diseasehighKidney disease requires renal review and monitoring.Low egfrhighReported low eGFR requires renal review.Abnormal creatininecautionAbnormal creatinine warrants renal monitoring.

Liver

Liver diseasehighLiver disease requires hepatic review and monitoring.Elevated astcautionReported elevated AST warrants hepatic monitoring.Elevated altcautionReported elevated ALT warrants hepatic monitoring.Elevated bilirubincautionReported elevated bilirubin warrants hepatic monitoring.

Metabolic

Uncontrolled glucosehighUncontrolled glucose requires metabolic review.DiabetescautionDiabetes or insulin resistance history may require metabolic monitoring.Insulin usecautionInsulin use warrants hypoglycemia and metabolic monitoring.Hypoglycemia historycautionHypoglycemia history warrants metabolic monitoring.Insulin resistancecautionInsulin resistance warrants metabolic monitoring.

Psychiatric

Suicidal ideation historycriticalSuicidal ideation history requires psychiatric safety review.Recent psychiatric hospitalizationhighRecent psychiatric hospitalization requires review.Psychosis historyhighPsychosis history requires psychiatric review.Bipolar disordercautionBipolar disorder warrants psychiatric review.

Neurological

Seizure historyhighSeizure history requires neurological review.Progressive neurological deficithighProgressive neurological deficit requires evaluation.Unexplained loss of consciousnesscautionUnexplained loss of consciousness warrants review.

Medication interaction

Blood thinnershighAnticoagulant/blood thinner use increases bleeding/interaction risk.ImmunosuppressantshighImmunosuppressant use requires interaction review.BiologicshighBiologic use requires interaction review.Psychiatric medicationscautionPsychiatric medication use warrants interaction review.Diabetes medicationscautionDiabetes medication use warrants interaction review.AntihypertensivescautionAntihypertensive use warrants interaction review.Polypharmacy flagcautionPolypharmacy increases interaction risk.

Reaction history

Anaphylaxis historycriticalAnaphylaxis history is a critical reaction-risk consideration.Injection reactionshighInjection reaction history may increase intolerance risk.Severe herxheimer like reactionshighHigh-reactivity or severe flare history may increase risk of intolerance.Mcas high reactivityhighMCAS/high-reactivity history may increase risk of intolerance.Medication allergiescautionMedication allergy history warrants reaction review.Supplement reactionscautionSupplement reaction history warrants reaction review.

Acute

Active feverhighActive fever warrants deferral and physician review.Acute infectionhighAcute infection warrants deferral and physician review.Recent hospitalizationhighRecent hospitalization requires physician review.Recent er visitcautionRecent ER visit warrants physician review.Unexplained weight losscautionUnexplained weight loss warrants physician review.

Current medications

One per line. Optionally add an interaction category after a pipe — e.g. warfarin | blood_thinner

Labs (optional)

eGFR

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